Organ Protection With Sevoflurane Postconditioning

Role of Volatile Anesthetics for Hepatic Protection in Ischemia-reperfusion: Postconditioning

Organ protection, volatile anesthetics, postconditioning, hepatic surgery

This study aims at the evaluation of a potential attenuation of ischemic-reperfusion injury in the liver with sevoflurane postconditioning upon reperfusion.

Inclusion criteria:

• older than 18 years
• patients undergoing liver resection (benign or malignant tumors)

Exclusion criteria:

• non-german speakers
• laparoscopic liver resection
• coagulopathy (platelets < 50'000/ml, Quick < 50%)
• liver cirrhosis