Intrauterine Embryo Development With ANECOVA Device

Multi-Center Evaluation Program NCVD1H Intrauterine Embryo'S Development Assisted by ANECOVA ACVd1 Device

We aim to compare the morphological and chromosomal features of human embryos cultured In Vitro versus those developed in a new In Vivo culture system with encapsulation in utero as well as implantation and pregnancy rate.

Inclusion Criteria:

• Women age below 37
• Hormonal serum levels within normal ranges (FSH, LH, E2, PRL, P4, T4, TSH)
• Negative serologic screening for HIV, Hep B and C
• No uterine or ovarian alterations found by ultrasound
• Normal BMI (19 - 29 kg/m2).

Exclusion Criteria:

• At least 8 stage MII oocytes are not retrieved
• Endometriosis or PCO
• Severe male factor in the partner