Immunogenicity After Two Doses of Meningococcal Outer Membrane Vesicle Vaccine MenBVac

EVALUATION DE LA REPONSE IMMUNITAIRE CONTRE LA SOUCHE DE NEISSERIA MENINGITIDIS B:14,P1.7,16

The main objective of the study is to estimate the proportion of children, born between the 01/01/2002 and the 06/23/200, living around Dieppe (cantons Dieppe est, Dieppe Ouest and Offranville), vaccinated by MenBVac, with a serum bactericidal activity against B:14,P1-7,16 clone related to a protection (>= 4), before and after the third MenBvac vaccination.

Inclusion Criteria:

• children born between 01/01/2000 and 06/23/2005, living in Dieppe-Est, Dieppe-Ouest and Offranville, vaccinated twice by MenBVac
• parental authority(ies)assent

Exclusion Criteria:

• no parental authority(ies)assent
• no blood sample during the third vaccination
• impossibility of third vaccination