Development of a New Method for Steady-State Measurement of NO Lung Diffusing Capacity in Healthy Subjects

Development of a New Method for Steady-State Measurement of NO Lung Diffusing Capacity in Healthy Subjects

Using a rapidly responding nitric oxide analyzer in a new developed modular lung-function-setup we are going to measure steady-state NO diffusing capacity in 107 healthy subjects (age 6-45 years). The results will be compared to those measured by using carbon monoxide single-breath estimates. We like to show that the new method is sufficient to measure exactly lung diffusion capacity in this collective.

Inclusion Criteria:

• Healthy volunteers
• Lung function testing possible
• Written consent

Exclusion Criteria:

• Pulmonary, neuromuscular, cardiovascular, endocrinological illness
• Pregnancy
• Abuse of nicotine, alcohol, drugs during the last two years