Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1

Phase 1, Double-Blind, Placebo-Controlled Multiple Dose Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine

The purpose of this study is to assess potential interactions between intravenous (i.v.) cocaine and atomoxetine (Strattera) administered orally in four escalating doses.

Inclusion Criteria:

• 18-45 years of age who are not seeking treatment at the time of the study
• Must be able to provide written informed consent
• Must be within 20 percent of ideal body weight and weigh at least 45 kg
• Must meet DSM0IV diagnostic criteria for cocaine abuse or dependence
• Must currently be using cocaine as confirmed by a positive BE
• If female and of child bearing potential, must agree to the use of birth control

Exclusion Criteria:

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