Assessment of Interactions Between Intravenous Methamphetamine and Modafinil - 1

Double-Blind, Placebo-Controlled Assessment of Interactions Between Intravenous Methamphetamine and Modafinil

The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral Modafinil.

The primary aims of this experiment are to determine if there are significant safety interactions between oral modafinil and intravenous methamphetamine. Safety will be assessed by measuring adverse events and cardiovascular responses of heart rate (HR), blood pressure (BP), and electrocardiogram (ECG) and stroke distance (ICG).

Inclusion Criteria:

• normotensive
• good physical and mental health
• body mass index between 18 and 30
• if female, using an acceptable method of contraception and are not pregnant
• able to give voluntary informed consent

Exclusion Criteria:

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