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| Name | Class |
|---|---|
| St. Olavs Hospital | OTHER |
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Does sucrose or pacifier influence pain in premature babies when a nasogastric tube is inserted?
A total of 24 premature babies are randomised to receive either placebo (sterile water), 30 % sucrose, or pacifier in a complete factorial, cross-over design. Pain is rated on the PIPP scale by observers blinded to the procedure other than use of pacifier.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | No Intervention | no fluid, no pacifier | |
| water | Experimental | water, no pacifier |
|
| sucrose | Experimental | Sucrose, no pacifier |
|
| pacifier | Experimental | No fluid, pacifier |
|
| water and pacifier | Experimental | water, pacifier |
|
| sucrose and pacifier | Experimental | sucrose, pacifier |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sucrose | Drug | 30 % sucrose |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Pain measured on PIPP (Premature Infant Pain Profile) scale | 4 week to complete |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Eirik Skogvoll, MD, PhD | Norwegian University of Science and Technology | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| St. Olavs University Hospital | Trondheim | Trondheim | N-7006 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 8722730 | Background | Stevens B, Johnston C, Petryshen P, Taddio A. Premature Infant Pain Profile: development and initial validation. Clin J Pain. 1996 Mar;12(1):13-22. doi: 10.1097/00002508-199603000-00004. | |
| 21536607 | Result | Kristoffersen L, Skogvoll E, Hafstrom M. Pain reduction on insertion of a feeding tube in preterm infants: a randomized controlled trial. Pediatrics. 2011 Jun;127(6):e1449-54. doi: 10.1542/peds.2010-3438. Epub 2011 May 2. |
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| ID | Term |
|---|---|
| D047928 | Premature Birth |
| D010146 | Pain |
| ID | Term |
|---|---|
| D007752 | Obstetric Labor, Premature |
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| ID | Term |
|---|---|
| D013395 | Sucrose |
| D041361 | Pacifiers |
| ID | Term |
|---|---|
| D004187 | Disaccharides |
| D009844 | Oligosaccharides |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
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| Pacifier |
| Device |
|
| sterile water | Other |
|
| D000091642 | Urogenital Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000073893 |
| Sugars |
| D015370 | Infant Equipment |
| D004864 | Equipment and Supplies |