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Sucking and sucrose have been shown to reduce pain during venous puncture in neonates. Our study is designed to see if sucking and sucrose relieve pain during venous puncture in infants age 3-12 months.
100 infants age 3-12 months old without neurologic, developmental or cardio-respiratory impairment, needing venous puncture for IV access, or blood aspiration, will be randomly assigned to one of 2 groups - with or without pacifier. During the puncture, each patient with pacifier will receive either 1 cc of water or 1 cc of sucrose (the solutions prepared and marked blindly) . Each patient without pacifier 2 will receive 1 cc of water without pacifier,will receive either 1 cc of water or 1 cc of sucrose (the solutions prepared and marked blindly). FLACC pain score will be used for apin assessment before, during and after the puncture.Comparison of the four groups will be done after the end of the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AW | No Intervention | no pacifier , no sucrose | |
| AS | Active Comparator | sucrose without pacifier |
|
| PW | No Intervention | ||
| PS | Experimental | Pacifier and sucrose interventional |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sucrose | Dietary Supplement | 1 cc of sucrose 33.5% with or without pacifier |
|
| Measure | Description | Time Frame |
|---|---|---|
| reduced pain scoring | 10 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| better Parent's scoring to the child's behavior | 10 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Vered Hofer, MD | Contact | 972-3-9253681 | veredho@clalit.org.il | |
| Rachel Efrat, MD | Contact | 972-3-9253279 | pedpain@clalit.org.il |
| Name | Affiliation | Role |
|---|---|---|
| Rachel Efrat, MD | Schneider Children's Medical Center, Israel | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Schneider Children's Medical Center of Israel | Petah Tikva | 49202 | Israel |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D013395 | Sucrose |
| ID | Term |
|---|---|
| D004187 | Disaccharides |
| D009844 | Oligosaccharides |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
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| D000073893 |
| Sugars |