The Effect of Sucrose on Pain Relief During Venous Blood Sampling in Preterm Infants

The Effect of Sucrose on Pain Relief During Venous Blood Sampling in Preterm Infants: a Comparison of Two Different Doses

Despite the fact that oral sucrose is the most frequently studied non-pharmacological intervention for procedural pain relief in infants, there is a paucity of data on the minimal effective dose. The aim of this study is to find the minimal effective dose of sucrose to reduce pain during a single venous blood sampling procedure.

Inclusion Criteria:

• born preterm
• more than 1000 gram

Exclusion Criteria:

• severe intraventricular hemorrhage
• cerebral malformations
• other malformations requiring surgery
• medication that may impair pain expression (opioids, paracetamol, sedatives)