Bispectral Index as an Analgesia Monitoring in Severely Ill Patient: Effect of Remifentanyl

Bispectral Index as an Analgesia Monitoring in Severely Ill Patient: Effect of Remifentanyl

The aim of this protocol is to study the prophylactic effect of remifentanil on bispectral index variation during a nociceptive stimuli.

Pain is difficult to estimate in ICU because most of the patients are sedated. Bispectral index could be helpful in detecting this pain in ICU patients. Remifentanil is a morphinomimetic product with short half life that could be interesting for short nociceptive stimuli, as bronchoalveolar lavage.

The purpose of this study is to evaluate the impact of remifentanil infusion on bispectral index (BIS) variations during bronchoalveolar lavage.

It is a prospective, double blind study, versus placebo on 40 sedated and critically ill patients.

The hypothesis is that BIS can study analgesia in sedated patient.

Inclusion Criteria:

• Sedated patient with mechanical ventilation with suspected nosocomial pneumonia

Exclusion Criteria:

• Pace maker
• Neurologic illness
• Hemodynamic instability
• Hypothermia