| ID | Type | Description | Link |
|---|---|---|---|
| DK50680-02 |
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The Decompression Intervention of Variceal Rebleeding Trial (DIVERT) is a multi-center prospective randomized clinical trial comparing the radiologic procedure of transjugular intrahepatic portal-systemic shunt (TIPS) with the surgical procedure of distal splenorenal shunt (DSRS) for variceal bleeding in patients with Child's Class A and B cirrhosis.
This is recognized nationally and internationally as the study that will answer the question as to which of these is the best treatment for decompression of varices in patients who have failed endoscopic and pharmacologic therapy.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transjugular Intrahepatic Portosystemic Shunt (TIPS) | Procedure | |||
| Distal Splenorenal Shunt | Procedure |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| J. Michael Henderson, M.D. | The Cleveland Clinic | Principal Investigator |
| Thomas D. Boyer, M.D. | Emory University | Principal Investigator |
| Lennox Jeffers, M.D. | University of Miami | Principal Investigator |
| Enrique Molina, M.D. | University of Miami | Principal Investigator |
| Layton F. Rikkers, M.D. | University of Wisconsin, Madison | Principal Investigator |
| Kareem Abu-Elmagd, M.D. | University of Pittsburgh Medical Center | Principal Investigator |
| Amrik Shah, Sc.D. | Cleveland Clinic Foundation - Data Coordinating Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Miami School of Medicine | Miami | Florida | 31336 | United States | ||
| Emory University |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18045724 | Derived | Boyer TD, Henderson JM, Heerey AM, Arrigain S, Konig V, Connor J, Abu-Elmagd K, Galloway J, Rikkers LF, Jeffers L; DIVERT Study Group. Cost of preventing variceal rebleeding with transjugular intrahepatic portal systemic shunt and distal splenorenal shunt. J Hepatol. 2008 Mar;48(3):407-14. doi: 10.1016/j.jhep.2007.08.014. Epub 2007 Oct 23. |
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| Atlanta |
| Georgia |
| 30322 |
| United States |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | United States |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | United States |
| University of Wisconsin | Madison | Wisconsin | 53792 | United States |
| ID | Term |
|---|---|
| D004932 | Esophageal and Gastric Varices |
| D008103 | Liver Cirrhosis |
| D014648 | Varicose Veins |
| D005355 | Fibrosis |
| D006975 | Hypertension, Portal |
| D008107 | Liver Diseases |
| ID | Term |
|---|---|
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D019168 | Portasystemic Shunt, Transjugular Intrahepatic |
| ID | Term |
|---|---|
| D011170 | Portasystemic Shunt, Surgical |
| D000714 | Anastomosis, Surgical |
| D013514 | Surgical Procedures, Operative |
| D058017 | Vascular Grafting |
| D014656 | Vascular Surgical Procedures |
| D013504 | Cardiovascular Surgical Procedures |
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