Observational Study of IgE-Mediated Leguminous Allergies in a Pediatric Population

Observational Study of IgE-Mediated Leguminous Allergies in a Pediatric Population

Prospective, monocentric, observational study with standard care follow-up during 5 years or until the patient reaches the age of 18.

The aim of this study is to prospectively and comprehensively assess the characteristics of patients aged 6 months to 17 years with leguminous allergy (excluding peanut) and their reactions to leguminous, including both medical history and prospective follow-up for 5 years from inclusion, or until the age of 18. The study aims to improve the understanding of these allergies, provide epidemiological data, and optimize diagnostic and clinical management. A biobank will also be established, with plasma (one whole blood sample collected at the inclusion) in order to validate future diagnostic tests.

Inclusion Criteria:

• Subjects aged 6 months to 17 years old
• Medical diagnosis of allergy to one or more leguminous :
• Clinical reaction following real-life exposure AND positive skin and/or biological sensitization
• Allergy confirmed by a positive oral food challenge (OFC) in cases of sensitization without a history of clinical reaction
• Subjects seen in a pediatric pneumo-allergy unit (consultation or hospitalization)

Exclusion Criteria:

• Isolated IgE-mediated peanut allergy
• Patients aged 18 years or older
• Minor patient or legal representant (parental authority) Refusal