MBI for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease

Mindfulness-based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease: Randomized Clinical Trial

This study examines the efficacy of a mindfulness-based intervention designed to support pain and sleep management in adolescents and young adults with sickle cell disease. Participants will be assigned to either an intervention or usual care group. Participants who are assigned to the intervention group will use a smartphone-based mindfulness program that includes structured modules and guided mindfulness exercises over an approximately 8-week period.

Inclusion Criteria:

• Individuals aged 15-39 years
• Have been diagnosed with SCD
• Are able to speak and understand English
• Are able to complete questionnaires with minimal or no assistance from a caregiver
• Report pain and/or sleep problems as assessed by the Adult Sickle Cell Quality of Life Measurement Information System (ASCQ-Me) short forms
• Have access to the internet on a smartphone, tablet, or computer

Exclusion Criteria:

• Individuals who have significant cognitive limitations that will impair their ability to use and understand the MBI, as per their health care provider or caregiver
• Are currently receiving an MBI or have received more than 4 sessions of any MBI in the 6 months prior to the screening