Intraoperative Glycemic Variability and Infectious Complications After Liver Transplantation

Intraoperative Glycemic Variability and the Risk of Infectious Complications After Elective Liver Transplantation: A Prospective Cohort Study

This study aims to evaluate whether intraoperative glycemic variability (GV) is independently associated with the risk of infectious complications within 30 days after elective liver transplantation. This is an observational study with no intervention beyond standard perioperative care. Glycemic and clinical outcome data will be obtained from routinely collected medical records of patients undergoing liver transplantation at the 2nd Department of Anesthesiology and Intensive Care, Medical University of Warsaw.

Inclusion Criteria:

• Age over 18 years
• Elective orthotopic liver transplantation

Exclusion Criteria:

• Liver retransplantation
• multi-organ transplantation
• Urgent/emergency transplantation
• Active infection under antibiotic treatment at the time of surgery
• Preoperative systemic inflammatory response syndrome (SIRS)
• Incomplete intraoperative glycemic data
• Pregnancy
• Participation in another interventional study that could affect glycemic control or infection risk