Intensive Glycemic Management and Outcomes Following Liver Transplantation

Intensive Glycemic Management and Outcomes Following Liver Transplantation: A Randomized Controlled Trial

Most people develop high blood sugars following liver transplant that requires treatment with insulin in the hospital, even if they don't have diabetes, due to stress and use of steroid medications. High blood sugar levels can be treated with a hormone that the body makes called insulin. This study is being done to determine if maintaining normal blood sugar levels after transplant for as long as needed while in the hospital results in a lesser incidence of death, infections, transplanted liver rejection or failure or need for rehospitalization within 90 days after transplant.

Inclusion Criteria:

• 18 years of age and older
• Undergoing liver transplant or combined liver-kidney transplant

Exclusion Criteria:

• Unable to grant informed consent or comply with study procedure
• Allergic to any of the excipients in insulin