Effects of a Synbiotic Intervention on Perimenopausal/Menopausal Symptoms

FemmeBiome Meno is a synbiotic supplement, meaning it contains both probiotics (beneficial bacteria) and prebiotics (a special kind of fiber that feeds these bacteria). It is made up of:

One capsule with 4 carefully selected bacterial strains and one sachet of powdered fiber.

Both the capsule and the fiber sachet are taken daily. There are also placebo versions (lookalike products with no active ingredients) for use in the clinical trial.

This specific combination of bacteria and fiber has not been studied before. However, previous research on the individual bacterial strains has shown several promising effects, such as:

Reducing inflammation in lab tests on vaginal cells.

Lowering stress-related hormones.

Supporting general feelings of well-being.

Helping maintain a healthy gut barrier, which is crucial for immune and digestive health.

The fiber helps nourish both the added bacteria and the helpful microbes already present in the body. Some of these bacteria are believed to be reduced during menopause, especially those involved in estrogen metabolism.

Why This Study Matters

The aim of this study is to see whether FemmeBiome Meno can ease some of the most common and disruptive symptoms of perimenopause and menopause. In a survey of over 100 women, the top concerns were:

Poor sleep

Anxiety

Brain fog (difficulty thinking clearly)

The study also aims to examine how the supplement affects gut and vaginal health, which are both influenced by the drop in reproductive hormones during this stage of life.

With so many women affected and such limited options currently available, there is a clear and urgent need for effective, science-backed natural solutions.

The FemmeBiome Meno study hopes to fill that gap by providing a validated product that can genuinely support women's health during midlife and beyond.