Outcome of Partial Pulpotomy in Permanent Mandibular Molars With Symptomatic Irreversible Pulpitis After Wound Lavage With Calcium Hypochlorite or... | NCT07748676

NCT07748676

Overview

NCT ID: NCT07748676
Lead Sponsor: Postgraduate Institute of Dental Sciences RohtakOTHER
Official Title: Outcome of Partial Pulpotomy in Permanent Mandibular Molars With Symptomatic Irreversible Pulpitis After Wound Lavage With Calcium Hypochlorite or Sodium Hypochlorite
Brief Summary: The aim of this randomised control trial is to compare the effect of wound lavage using 2.5% Ca(OCl)₂ and 2.5% NaOCl on the outcome of partial pulpotomy in mature permanent mandibular molars with symptomatic irreversible pulpitis (SIP).Primary objective is to evaluate and compare clinical and radiographic outcome of partial pulpotomy following use of 2.5% Ca(OCl)₂ and 2.5% NaOCl in mature permanent mandibular molars with symptomatic irreversible pulpitis.secondary objective is to evaluate OHRQoL and pain experience after use of 2.5% Ca(OCl)₂ and 2.5% NaOCl during partial pulpotomy in permanent mandibular molars with clinical signs indicative of symptomatic irreversible pulpitis.
Conditions: Symptomatic Irreversible Pulpitis (SIP)

Status and Timeline

Status: Recruiting
Last Update Posted: Aug 6, 2026Actual
Start Date: Apr 29, 2026Actual
Primary Completion Date: Oct 28, 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

patients aged 18-40 years

Mature permanent mandibular molars with extremely deep caries (caries penetrating the entire thickness of the dentine radiographically, without radiopaque zone separating lesion from the pulp) and clinical diagnosis of SIP with PAI score ≤ 2

Periodontally healthy teeth (probing pocket depth ≤3 mm and mobility within normal limit)

Patients having physical status of class 1 or 2 according to ASA classification

Pulpal bleeding could be controlled within 10 min following pulp amputation

Exclusion Criteria:

Non restorable teeth

No pulp exposure even after complete caries excavation

Necrotic or partially necrotic pulp upon exposure

Presence of sinus tract or soft tissue swelling

Radiographic signs of internal or external root resorption

Pregnant women

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 106Estimated
Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking

Contacts and Locations

Central Contacts: Dr. Mayank Arora, MDSContact
dr.arora002@gmail.com

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