Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion | NCT07746700

NCT07746700

Overview

NCT ID: NCT07746700
Lead Sponsor: Al-Azhar UniversityOTHER
Official Title: Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion
Brief Summary: This prospective clinical trial aims to evaluate the clinical and radiographic outcomes of the low sagittal medial ramus osteotomy-a technical modification of the conventional sagittal split osteotomy (SSO)-for treating patients with skeletal Class II and Class III malocclusions.

Standard sagittal split osteotomies carry risks of complications, including unfavorable osteotomy propagation (bad splits) toward the condyle, ramus fragmentation, lingual interference of the distal segment, and inferior alveolar nerve (IAN) injury. To minimize these risks, this study utilizes a modified medial cut positioned low (below the lingula in an area with adequate marrow space) and short (terminating anterior to the lingula). This design aims to prevent osteotomy extension into the condylar region and eliminate lingual interference during segment repositioning.
Conditions

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Aug 5, 2026Actual
Start Date: Sep 2026Estimated
Primary Completion Date: Apr 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Patients with skeletal Class II or Class III malocclusion requiring mandibular orthognathic surgery.

Age range from 18 to 45 years old.

Systematically healthy patients classified as ASA physical status I or II (American Society of Anesthesiologists)

Exclusion Criteria:

Patients with a pre-existing history of inferior alveolar nerve (IAN) sensory impairment.

Patients with active or severe degenerative joint disease (DJD).

Patients with a prior history of orthognathic surgical procedures.

Patients presenting with systemic diseases or conditions known to compromise normal bone healing.

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 11Estimated
Primary Purpose: Treatment
Allocation: N/A
Interventional Model: Single Group Assignment
Masking

Contacts and Locations

Central Contacts: No data available
Locations: No data available

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