Objective: Titanium-prepared platelet-rich fibrin (T-PRF) has emerged as a promising biomaterial in periodontal regenerative procedures. The aim of this study will be to compare the clinical effectiveness of de-epithelialized gingival grafts (DGG) and T-PRF in the reconstruction of deficient interdental papillae using the tunnel technique.
Methods: A total of 34 patients presenting with 115 Class I and II interdental papilla defects will be enrolled in this study. Interdental papilla reconstruction will be performed using the tunnel technique in combination with either DGG or T-PRF. Demographic characteristics (age and sex), dentogingival variables (tooth shape, papilla location, jaw type, and papilla loss classification), and clinical parameters will be recorded. Clinical assessments will include probing depth (PD), gingival index (GI), plaque index (PI), gingival thickness (GT), keratinized tissue height (KTH), black triangle width (BTW), black triangle height (BTH), papilla fill percentage (%PF), and black triangle area (BTA). All clinical parameters will be assessed at baseline and at 1, 3, and 6 months following surgery.
Inclusion Criteria:
Exclusion Criteria:
Participants assigned to this group received papilla reconstruction using a de-epithelialized gingival graft harvested from the palatal mucosa. Following tunnel preparation via the tunnel technique, the graft was de-epithelialized to a thickness of approximately 1.5 mm and inserted beneath the papillary flap to fill the defect. Graft stabilization and coronal advancement of the flap were achieved using suspension sutures anchored to preoperatively placed composite splints.
In this group, T-PRF membranes were prepared by centrifuging autologous blood in grade IV titanium tubes at 2,800 rpm for 12 minutes. The resulting fibrin clots were compressed to create standardized membranes, which were folded and placed into the prepared tunnel beneath the papilla. Similar to the DGG group, the flap was coronally repositioned and stabilized using suspension sutures attached to composite splints.
Denizli, Denizli 20160, Turkey (Türkiye)
Comparison of the Efficacy of Platelet-rich Fibrin and Connective Tissue Graft in Interdental Papilla Reconstruction
A Clinical Comparison of Connective Tissue Graft and Alb-PRF for Rebuilding Interdental Papilla
Comparison of Connective Tissue Graft Versus Titanium Papillary Inserts in the Surgical Reconstruction of Interdental Papilla.
The Effectiveness of Titanium-Prepared Platelet-Rich Fibrin on Angiogenic Biomarkers in Gingival Crevicular Fluid
Comparative Evaluation of Alb PRF Versus Connective Tissue Graft in Reconstruction of Deficient Interdental Papilla
Platelet-Rich Fibrin Prepared With Titanium in the Treatment of Multiple Gingival Recessions