Inclusion Criteria:

1. Subjects aged ≥45 years, regardless of gender;
2. Subjects undergoing screening colonoscopy;
3. Subjects with no prior colonoscopy;
4. Voluntarily provide written informed consent.

Exclusion Criteria:

1. Subjects unable to cooperate with or tolerate colonoscopy;
2. Subjects with inflammatory bowel disease;
3. Known or highly suspected colorectal obstruction;
4. History of colorectal surgery;
5. Chronic recurrent constipation;
6. Failure to discontinue anticoagulants or antiplatelet agents for at least 1 week before the procedure;
7. Poor bowel preparation with an inadequate Aronchick scale score during colonoscopy;
8. Failed cecal intubation;
9. High-risk conditions including severe cardiovascular and cerebrovascular diseases, uncorrected severe anemia or active infection;
10. Pregnant or breastfeeding women;
11. Subjects deemed ineligible for participation in this trial at the investigator's discretion.