CRPS-Hand: Contrast + Compression vs Whirlpool | NCT07744269

NCT07744269

Overview

NCT ID: NCT07744269
Lead Sponsor: Ankara Etlik City HospitalOTHER_GOV
Official Title: Combined Contrast Therapy and Intermittent Compression vs Whirlpool Therapy in Post-Traumatic Hand and Wrist CRPS: A Randomized Controlled Trial
Brief Summary: This randomized controlled trial aims to evaluate and compare the effectiveness of combined contrast therapy with intermittent compression and whirlpool therapy in patients with post-traumatic CRPS-I of the hand and wrist, using objective outcome measures of pain, edema, and functional status.
Conditions: Complex Regional Pain Syndrome I (CRPS I)
Interventions: Combined Contrast Therapy with Intermittent Compression

Status and Timeline

Status: Recruiting
Last Update Posted: Aug 4, 2026Actual
Start Date: May 1, 2026Actual
Primary Completion Date: Apr 30, 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Patients diagnosed with Complex Regional Pain Syndrome Type 1 (CRPS-I) according to the Budapest Criteria

Age between 18 and 80 years

CRPS developed following upper extremity trauma (e.g., hand or wrist fracture, soft tissue injury)

Symptom duration less than 3 months (subacute stage)

Ability and willingness to provide written informed consent and voluntarily participate in the study

Exclusion Criteria:

Patients diagnosed with Complex Regional Pain Syndrome Type 2 (CRPS-II) or with evidence of peripheral nerve injury

History of peripheral neuropathy, Raynaud's phenomenon, or vascular circulation disorders

Presence of impaired skin integrity, open wounds, infection, or dermatological disease in the affected area

History of cold or heat intolerance, cold urticaria, or hypersensitivity to thermal modalities

Active infection or severe edema in the affected extremity

Presence of serious systemic diseases (cardiovascular, pulmonary, renal, or neurological)

Receipt of similar physical therapy or modality-based treatment within the past 3 months

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 50Estimated
Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking

Contacts and Locations

Central Contacts: Gizem Suna Tuncer, MD, Specialist PhysicianContact
sunagizem05@gmail.com

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