Monitoring of Neuromuscular Blockade in the Intensive Care Unit: a Reliability Study | NCT07741851

NCT07741851

Overview

NCT ID: NCT07741851
Lead Sponsor: Centre Hospitalier Intercommunal Aix-PertuisOTHER
Official Title: Monitoring of Neuromuscular Blockade in the Intensive Care Unit: a Reliability Study
Brief Summary: The objective of this clinical trial is to evaluate the reliability of neuromuscular blockade monitoring in adult intensive care patients depending on the clinical context.

The main questions it aims to answer are as follows:

Detection of an anomaly at ulnar "TOF" stimulation in patients without neuromuscular blockade

Absence of adverse events during clinical monitoring of neuromuscular blockade (every 24 hours): absence of respiratory effort movements or patient-ventilator asynchrony (safety)
Conditions: Neuromuscular Blockade Monitoring
Interventions

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Adult patients

Patients admitted to the intensive care unit who have been receiving neuromuscular blocking agents for at least 24 hours during their stay - Consent obtained from the patient or emergency consent obtained from family members

Patients covered by the French social security system, regardless of the specific plan

Exclusion Criteria:

Patients who have already been exposed to prolonged neuromuscular blockade or who have been receiving continuous neuromuscular blockade for less than 24 hours

Allergy to neuromuscular blocking agents

Patients with a neurological condition that alters the interpretation of neuromuscular blockade or contraindicates the use of neuromuscular blocking agents

Patients enrolled in an interventional study

Patients who object to the collection of their medical data for this study

Patients under the age of 18

Patients deprived of their liberty, under guardianship, or under conservatorship

Pregnant or breastfeeding women