Comparison of Two Neuromuscular Transmission Monitors Based on Acceleromyography: TOF-Watch SX® and TOFScan®

Comparison of Two Neuromuscular Transmission Monitors Based on Acceleromyography: TOF-Watch SX® and TOFScan®

The purpose is to evaluate the reproducibility of neuromuscular monitoring data of recovery from neuromuscular blockade, obtained with TOFScan® and TOF-Watch SX®, in adult and pediatric population.

Secondary purposes are to evaluate the reproducibility of data obtained with 2 monitors for:

• the onset of clinical action of curare: suppression of the first response of train of four monitoring (T1) of 95% initial value
• the duration of clinical action of curare: recovery of the first response of train of four monitoring (T1) to 25% initial value
• recovery of first (T1), second (T2), third (T3) and fourth response (T4) of train of four monitoring, and recovery of T4/T1 to 40% and 60% initial value (T4/T1 0.4 and 0.6)
• complete recovery from curarisation, at T4/T1=90% and T4/T1=100%.

Inclusion Criteria:

Adult population:

• Non opposition to research
• > 18 years old
• ASA score 1-3
• Undergoing surgery with curarisation through tracheal intubation
• Affiliation to social security

Pediatric population:

• > 1 year old
• Non opposition to research of child (if able to consent) or representatives with parental authority
• ASA score 1-4
• Undergoing surgery with curarisation
• Affiliation to social security

Exclusion Criteria:

Adult population:

• Allergy to administered drugs
• Known or suspected difficult intubation
• Pregnant women
• BMI > 40

Pediatric population:

• Allergy to administered drugs
• Known or suspected difficult intubation