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NCT07733167

Overview

NCT ID: NCT07733167
Lead Sponsor: Benha UniversityOTHER
Official Title: Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate: Exploring Its Role in Optimizing Surgical Outcomes
Brief Summary: Intra-Prostatic Epinephrine injection in Bipolar Transurethral resection of large prostate: Exploring Its Role in Optimizing Surgical Outcomes
Conditions: Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate
Interventions: TURP
Epinephrine

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: Male
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Indication for Prostate Surgery or Procedure - Patients undergoing transurethral resection of the prostate (TURP)

Prostate from 80 to 100 gm

Failed medical therapy

Exclusion Criteria:

Uncontrolled Hypertension - Patients with significantly high blood pressure despite medication therapy.

Unstable angina, recent myocardial infarction, arrhythmias, or severe heart failure.

Significant Coagulopathy - Patients with bleeding disorders or on anticoagulants where excessive vasoconstriction may lead to tissue necrosis or inadequate perfusion

Hyperthyroidism, Pheochromocytoma or Endocrine Disorders - Patients with catecholamine-secreting tumors or other conditions that can lead to excessive sympathetic stimulation.

Treatment in the last 3 months with 5-alpha reductase inhibitors.

Genitourinary cancer, urinary tract lithiasis, and urological surgery within the last 3 months