Establishing the Glycaemic Index of Vegetable Smoothies | NCT07729631

NCT07729631

Overview

NCT ID: NCT07729631
Lead Sponsor: University of BathOTHER
Official Title: Study to Establish Glycaemic Response to the Ingestion of Vegetable Smoothies Expressed as Glycaemic Index Following Best Practice Guidelines
Brief Summary: Glycaemic responses to carbohydrates ingested as fruit and vegetables may vary depending on factors inherent to the fruit or vegetable, and on the type of sugar. The aim of this project is to investigate the glycaemic responses to two new fruit and vegetable smoothies, and to establish the glycaemic index for each product relative to a glucose reference. Participants will undertake 4 postprandial tests with 2 different test drinks following best practice guidelines for glycaemic index testing. The test drinks (GREEN and RED) will be matched for carbohydrate to the glucose reference (CONTROL) which will be sampled two times. Fingerstick capillary blood sampling will measure glucose concentrations. These data will provide insight into how differing formulations can alter the glycaemic responses to fruit and vegetable drinks.
Conditions

Status and Timeline

Status: Completed
Last Update Posted: Jul 27, 2026Actual
Start Date: Oct 22, 2025Actual
Primary Completion Date: Dec 15, 2025Actual
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion Criteria:

Age: 18-65 years

Body mass index 18-30 kg/m2

Exclusion Criteria:

diagnosis of any form of diabetes

intolerances or allergies to any of the study procedures (e.g. fructose/inulin intolerance)

Fructose malabsorption

Inborn errors of fructose metabolism (e.g. fructokinase deficiency, aldolase B deficiency, fructose-1,6-bisphosphatase deficiency)

pregnant or lactating

any condition that could introduce bias to the study (e.g. diagnoses of lipid disorders, including cardiovascular disease, or therapies that alter lipid or glucose metabolism, such as statins or niacin).

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 16Actual
Primary Purpose: Basic Science
Allocation: Randomized
Interventional Model: Crossover Assignment
Masking: None (Open Label)

Contacts and Locations

Central Contacts: No data available
Locations: Department for Health, University of Bath

Similar Studies

Participant Group/Arms

CONTROLActive Comparator

50 g glucose (55 g dextrose powder accounting for hydration) plus 519 mL water

Other: Vegetable Smoothie

REPLICATE CONTROLActive Comparator

50 g glucose (55 g dextrose powder accounting for hydration) plus 519 mL water

Other: Vegetable Smoothie

REDExperimental

500 mL of commercially available "Red Goodness" providing 50 g of carbohydrate \[apple (47%), banana, chayote (8%), beetroot (7%), carrot (5%), cucumber (5%), cherry (3%), spinach (2%), mandarin, lemon, apple water, beetroot extract\]. Plus 19 mL water to standardise volume

Other: Vegetable Smoothie

GREENExperimental

519 mL of commercially available "Green Goodness" smoothie providing 50 g carbohydrate \[apples (46%), banana, courgette (10%), chayote (8%), guava, cucumber (5%), lemon (3%), spinach (2%), mandarin, apple water spirulina extract, turmeric extract, mint extract\].

Other: Vegetable Smoothie