Knee osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage wear, leading to pain, stiffness, and joint swelling. It is highly prevalent in aging populations and is strongly associated with obesity and previous joint injury. OA affects millions of individuals worldwide, with incidence and prevalence increasing markedly with age and resulting in significant functional disability
The primary therapeutic goals in the management of knee osteoarthritis are pain reduction and improvement of joint mobility.
Total knee arthroplasty is considered one of the most effective surgical interventions for relieving pain and restoring function in patients with severe knee osteoarthritis. Nevertheless, residual pain and limited functional improvement remain the most frequent causes of patient dissatisfaction following TKA
Genicular nerve radiofrequency ablation (GNRFA) has emerged as an innovative treatment option for symptomatic knee osteoarthritis. This technique has been shown to reduce pain and improve function, with clinical benefits often observed as early as one week after treatment. GNRFA consistently provides short-term pain relief (3 to 6 months) and, in some cases, longer-lasting benefits.
The hypothesis tested in this study is whether GNRFA performed at least two weeks preoperatively can reduce postoperative pain and improve postoperative function.
Inclusion Criteria:
AND either of:
Exclusion Criteria:
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Patients in this arm will receive genicular nerve radiofrequency ablation between 2 to 6 weeks before undergoing elective total knee replacement
Patients in this group will not receive any intervention before undergoing elective total knee replacement
Total Knee Arthroplasty in Conjunction With Intra-operative Genicular Nerve Radio-Frequency Ablation
Genicular Radiofrequency Ablation Efficacy in Achieving Total Knee Pain Reduction Trial
Radiofrequency For Chronic Knee Pain Post-Arthroplasty
Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes
Genicular Radiofrequency Ablation Following Total Knee Arthroplasty
The Effect of Radiofrequency Ablation on the Results of the Genicular Nerve Number in the Treatment of Knee Osteoarthritis
The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty
Genicular Nerve Radiofrequency Ablation for Chronic Knee Pain After Total Knee Arthroplasty