Modified External Oblique Intercostal Plane Block Versus Erector Spinae Plane Block for Open Nephrectomy | NCT07726550

NCT07726550

Overview

NCT ID: NCT07726550
Lead Sponsor: Namik Kemal UniversityOTHER
Official Title: Comparison of Modified External Oblique Intercostal Plane Block and Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Open Nephrectomy: A Prospective Randomized Controlled Trial
Brief Summary: This prospective, randomized, assessor-blinded clinical trial aims to compare the postoperative analgesic efficacy of ultrasound-guided Erector Spinae Plane Block (ESPB) and Modified External Oblique Intercostal Plane Block (EOIPB) in patients undergoing elective open nephrectomy under general anesthesia. Sixty adult patients will be randomized to receive either ESPB or EOIPB before surgical incision. All participants will receive standardized general anesthesia and postoperative multimodal analgesia. Postoperative pain scores, opioid consumption, rescue analgesic requirements, and postoperative nausea and vomiting will be assessed during the first 24 hours after surgery. The study aims to determine whether one fascial plane block technique provides superior postoperative pain control and recovery following open nephrectomy.
Conditions

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Jul 24, 2026Actual
Start Date: Aug 1, 2026Estimated
Primary Completion Date: Feb 1, 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Age between 18 and 65 years.

American Society of Anesthesiologists (ASA) physical status I or II.

Scheduled for elective open nephrectomy.

Able and willing to provide written informed consent.

Willing to comply with study procedures.

Exclusion Criteria:

Refusal to participate or inability to provide informed consent.

Emergency surgery.

Body mass index (BMI) greater than 35 kg/m².

Known allergy or hypersensitivity to local anesthetics.

Infection at the planned block insertion site.

Coagulopathy or ongoing anticoagulant therapy.

Pregnancy or breastfeeding.

Prisoners or other vulnerable populations unable to provide independent consent.

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 60Estimated
Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Double

Contacts and Locations

Central Contacts: Onur Baran, MDContact
dronurbaran@hotmail.com+90 539 342 25 82

Similar Studies

Participant Group/Arms

ESPB GroupExperimental

Participants will receive an ultrasound-guided erector spinae plane block with 30 mL of 0.25% bupivacaine after induction of general anesthesia and before surgical incision. Standardized general anesthesia and postoperative multimodal analgesia will be provided to all participants.

Procedure: Erector Spinae Plane Block

EOIPB GroupExperimental

Participants will receive an ultrasound-guided modified external oblique intercostal plane block with 30 mL of 0.25% bupivacaine after induction of general anesthesia and before surgical incision. Standardized general anesthesia and postoperative multimodal analgesia will be provided to all participants.

Procedure: Modified External Oblique Intercostal Plane Block