Troponin elevation can, among others, be due to myocardial infarction, acute inflammation or structural heart disease. Formation of macrocomplexes against troponin is an underestimated cause for persistent troponin elevation. Polyethlylene glycol precipitation (PEG) can differentiate macrotroponin from real troponin elevation, but cut-off values for PEG have not been established. PEG is analyzed in patients with acute coronary syndrome undergoing invasive coronary angiography and compared to healthy marathon runners who have undergone cardiological pre-participation screening and have rested for 24 hours.
Inclusion Criteria:
Exclusion Criteria:
simon.wernhart@gmx.de+491751830099
There is no option to mask patients are investigators
Marathon runners are expected to have no elevated troponin at baseline after 24 hours of rest
Troponin will be elevated in acute coronary syndrome per definition
sebastian.zenk@synlab.com+49821227800
TREAT Study - Improving the Interpretation of Troponin Concentrations Following Exercise and Their Clinical Significance
Mersey Acute Coronary Syndrome Rule-Out Using High Sensitive Troponin
Exercise Test and Cardiac Injury
Cardiac Troponin Fragmentation After Heavy Physical Exercise The MaraCat2 Study
Troponin POCT in the Diagnosis of an Acute Myocardial Infarction
Troponin T in Chronic Obstructive Pulmonary Disease (COPD) Patients After Physical Exercise
Effect of Point-of-care Analysis of Ultrasensitive Troponin I on Length of Hospital Stay in Patients With Cardiac Chest Pain (POC Troponina)
Prehospital Risk Stratification in Acute Coronary Syndromes