Structured Inpatient Physiotherapy in High-Risk Coronary Artery Bypass Grafting Patients | NCT07725887

NCT07725887

Overview

NCT ID: NCT07725887
Lead Sponsor: Bezmialem Vakif UniversityOTHER
Official Title: Effect of a Preoperatively Initiated Structured Inpatient Physiotherapy Program on Postoperative Outcomes in High-Risk Coronary Artery Bypass Grafting Patients
Brief Summary: Coronary artery bypass grafting (CABG) may be associated with prolonged recovery, particularly in high-risk patients. Although preoperative rehabilitation has shown promising results, evidence remains limited because of heterogeneous intervention protocols and variations in postoperative care. This study aims to investigate the effects of a structured inpatient physiotherapy program initiated at least two days before surgery and continued postoperatively, compared with the same structured physiotherapy program provided only during the postoperative period, in high-risk CABG patients. The primary outcome is hospital length of stay. Secondary outcomes include intensive care unit length of stay, C-reactive protein, neutrophil-to-lymphocyte ratio, hemoglobin, dyspnea, and fatigue.
Conditions

Status and Timeline

Status: Recruiting
Last Update Posted: Jul 24, 2026Actual
Start Date: Jul 22, 2026Actual
Primary Completion Date: Jan 2, 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Adults aged 18 years or older.

Scheduled to undergo elective coronary artery bypass grafting (CABG).

High-risk patients meeting at least three of the following criteria:

Left ventricular ejection fraction (LVEF) <40%. Three-vessel coronary artery disease. More than two comorbidities. History of smoking. Age >65 years.

- Able and willing to provide written informed consent.

Exclusion Criteria:

Planned redo CABG surgery.

Severe neurological or orthopedic conditions limiting mobilization.

Severe cognitive impairment.

Hemodynamic instability.

Contraindications to mobilization or exercise.

Inability to complete at least two days of the preoperative physiotherapy program.

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 100Estimated
Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: None (Open Label)

Contacts and Locations

Central Contacts: Fuat Gökdemir, PT, MScContact
fuat.gokdemir@bezmialem.edu.tr+905543727084

Similar Studies

Participant Group/Arms

Preoperative and Postoperative Structured Inpatient PhysiotherapyExperimental

Participants will receive a structured inpatient physiotherapy program initiated at least two days before CABG surgery and continued throughout the postoperative hospitalization. The program includes breathing exercises, incentive spirometry, bronchial hygiene techniques, progressive early mobilization, and postural exercises. One supervised session will be provided daily before surgery, and participants will be instructed to repeat the program independently twice daily.

Other: Preoperative and Postoperative Structured Inpatient Physiotherapy

Postoperative Structured Inpatient PhysiotherapyActive Comparator

Participants will receive the same structured inpatient physiotherapy program only during the postoperative hospitalization. The program includes breathing exercises, incentive spirometry, bronchial hygiene techniques, progressive early mobilization, and postural exercises. No preoperative physiotherapy will be provided.

Other: Postoperative Structured Inpatient Physiotherapy