Multiple Micronutrient Versus Iron-Folic Acid Supplementation in Pregnant Women in Indonesia | NCT07725549

NCT07725549

Overview

NCT ID: NCT07725549
Lead Sponsor: Indonesia Timur UniversityOTHER
Official Title: Effect of Multiple Micronutrient Supplementation Versus Iron and Folic Acid Supplementation on Maternal Nutritional Biomarkers and Birth Outcomes Among Pregnant Women in Indonesia
Brief Summary: Micronutrient deficiencies during pregnancy may affect the mother's nutritional status and the baby's growth. This study compared two types of daily supplements for pregnant women: a multiple micronutrient supplement and an iron and folic acid supplement.

Pregnant women in Indonesia who were at 12 weeks of gestation or earlier were randomly assigned to receive one of the two supplements for eight weeks. The study measured maternal body weight, mid-upper arm circumference, hemoglobin concentration, and serum zinc concentration before and after supplementation. Infant birth weight and the occurrence of low birth weight were assessed after delivery.

The purpose of the study was to determine whether multiple micronutrient supplementation produced greater improvements in maternal nutritional indicators and birth outcomes than iron and folic acid supplementation.

Status and Timeline

Status: Completed
Last Update Posted: Jul 24, 2026Actual
Start Date: Jul 10, 2025Actual
Primary Completion Date: Dec 25, 2025Actual
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)
Sexes Eligible for Study: Female
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Pregnant women at 12 weeks of gestation or earlier Aged 18 to 40 years No diagnosed chronic disease Willing to complete all study procedures Provided written informed consent

Exclusion Criteria:

Severe pregnancy complications Known allergy to any supplement ingredient Inability to communicate adequately with the research team Planned relocation from the study area within the following six months

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 66Actual
Primary Purpose: Prevention
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Double

Contacts and Locations

Central Contacts: No data available
Locations: Puskesmas Grobogan

Similar Studies

Participant Group/Arms

Multiple Micronutrient SupplementationExperimental

Participants assigned to this arm received one multiple micronutrient supplement daily for eight weeks.

Dietary Supplement: Multiple micronutrient supplementation

Iron and Folic Acid SupplementationActive Comparator

Participants assigned to this arm received one iron and folic acid supplement daily for eight weeks according to the applicable antenatal supplementation standard.

Dietary Supplement: Iron and Folic Acid Supplementation