The 1000 First Day of Life : Effect of Multi Micronutrients Supplementation on Pregnancy Outcomes

The 1000 First Day of Life : Effect of Multi Micronutrients Supplementation on Pregnancy Outcomes

To monitor the effects of multi micronutrients supplementations during pregnancy towards pregnancy outcomes

A randomized control trial of two clusters :

1st cluster without giving multi micronutrients; 2nd cluster giving multi micronutrients.

Differences between cluster : Additional multi micronutrients by giving : Complete multi micronutrients, calcium, vitamin D and DHA. The additional multi micronutrients were given since 1st until 3rd trimester for interventions group. There are also additional laboratory examinations for intervention group : Vitamin D, Lipid Profile and Zinc level.

In control group : we use standard public health care micronutrients (Iron supplementation and calcium); and standard blood examinations.

Ultrasound examination was performed for both cluster since 1st until 3rd trimester.

Inclusion Criteria:

• First trimester pregnancy
• Gestational age < 10 weeks gestation
• Agree as research participant
• Living in DKI Jakarta

Exclusion Criteria:

• Assisted Reproductive
• History of PCOS
• History of Chronic Hypertension
• History of Diabetes Mellitus
• History of Preeclampsia
• Maternal chronic disease : Cardiovascular disease; Autoimmune condition; Malignancy)
• Plan to move from Jakarta prior or during pregnancy
• History of Recurrent pregnancy loss