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NCT07723027

Overview

NCT ID: NCT07723027
Lead Sponsor: Lahore University of Biological and Applied SciencesOTHER
Official Title: Effects of Whole Body Vibration Versus Proprioceptive Neuromuscular Facilitation Pattern With Rhythmic Based Training on Clinical Outcomes in Patients With Parkinson's Disease.
Brief Summary: This study has important clinical, academic, and practical relevance in neuromuscular rehabilitation. Clinically, it aims to identify effective and tolerable rehabilitation strategies for individuals with Parkinson's disease by comparing whole-body vibration therapy with proprioceptive neuromuscular facilitation (PNF) patterns combined with rhythmic-based training, thereby supporting evidence-based physiotherapy practice and improving patient adherence. Academically, it contributes to the limited literature on comparative effectiveness of these interventions and incorporates patient-centered outcomes such as exercise perception, which are often underreported. From a practical and societal perspective, identifying a more acceptable and effective approach may enhance long-term participation in rehabilitation, potentially slow disease progression, improve quality of life, and reduce the overall healthcare burden associated with Parkinson's disease.

Status and Timeline

Status: Completed
Last Update Posted: Jul 23, 2026Actual
Start Date: May 1, 2026Actual
Primary Completion Date: Jul 9, 2026Actual
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Age between 40 and 60 years.

Patients of both genders (male and female).

Parkinson's disease severity at Hoehn and Yahr (H&Y) stage 2 and 3.

Ability to walk independently for 6 minutes without an assistive device.

Score greater than 40 on the Berg Balance Scale.

Exclusion Criteria:

Presence of impaired Cognition.

Significant Orthopedic and Musculoskeletal conditions that limit the adherence to exercise and WBV requirements.

Other medical conditions like thrombosis, cardiovascular conditions and medical implants that are contradicted for WBV.

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 42Actual
Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Double

Contacts and Locations

Central Contacts: No data available
Locations: THQ Shakargarh

Similar Studies

Participant Group/Arms

Whole Body Vibration with Rhythmic Based TrainingExperimental

Whole Body Vibration (WBV) and Rhythm-Based Training (RBT) are adjunct therapeutic interventions used to enhance functional mobility, balance, and motor coordination. WBV provides mechanical oscillatory stimuli to the body through a vibration platform, aiming to improve neuromuscular activation and postural control. RBT utilizes external auditory cues to guide movement timing, promoting auditory-motor entrainment and improving movement coordination and gait performance.

Other: Whole Body Vibration with Rhythmic Based Training

Proprioceptive Neuromuscular Facilitation Pattern with Rhythmic Based TrainingExperimental

Proprioceptive Neuromuscular Facilitation (PNF) Rhythmic Initiation (RI) D1 patterns combined with Rhythm-Based Training (RBT) are used to facilitate motor learning, improve movement initiation, and enhance neuromuscular coordination. The D1 flexion and extension patterns of PNF target coordinated multi-planar upper and lower limb movements, progressing through passive, active-assisted, and active-resistive phases to improve motor control, normalize muscle tone, and increase movement efficiency. RBT provides external auditory cueing to enhance timing and rhythmic synchronization of voluntary movement.

Other: Proprioceptive Neuromuscular Facilitation Pattern with Rhythm-Based Training