Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation Syndrome | NCT07722247

NCT07722247

Overview

NCT ID: NCT07722247
Lead Sponsor: Kata CulinaOTHER
Official Title: Influence of Corneal Biomechanics on Surgically Induced Astigmatism After Cataract Surgery in Patients With Pseudoexfoliation Syndrome
Brief Summary: This prospective study aims to evaluate the influence of corneal biomechanical properties on surgically induced astigmatism following standard phacoemulsification cataract surgery in patients with pseudoexfoliation syndrome compared with patients without pseudoexfoliation. Corneal hysteresis (CH), corneal resistance factor (CRF) and corneal astigmatism will be measured before surgery and at postoperative follow-up visits. The relationship between changes in corneal biomechanics and surgically induced astigmatism will be analyzed.
Conditions: Pseudoexfoliation Syndrome
Cataract
Astigmatism

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Adults aged 50-85 years

Age-related cataract scheduled for standard phacoemulsification cataract surgery with intraocular lens implantation

Presence of pseudoexfoliation syndrome (PEX group) or absence of pseudoexfoliation syndrome (control group)

Ability to provide written informed consent

Willingness to attend all scheduled postoperative follow-up visits

Exclusion Criteria:

Previous ocular surgery in the study eye

Corneal diseases or abnormalities that may affect corneal biomechanical measurements or keratometry

Glaucoma and ocular hypertension

Ocular trauma or active ocular inflammation