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To evaluate the refractive outcomes of cataract surgery in PEX syndrome and determine which of the commonly used IOL formulas (SRK/T, Barrett Universal II and Hill-RBF) is the best in predicting postoperative refractive outcomes in PEX.
The primary outcome measure was to compare refractive outcomes (MAE, MedAE, percentage of eyes within certain range of prediction error) in PEX and control eyes. The secondary outcome measure was to determine whether any of IOL power prediction formulas (SRK/T, Barrett Universal II and Hill-RBF) is more precise for these challenging eyes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PEX | 42 eyes with PEX syndrome and coexisting cataract |
| |
| Control | 38 eyes with cataract only |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Phacoemulsification cataract surgery | Procedure | All surgeries were performed using Infinity (Alcon Laboratories, Inc.) under topical anaesthesia by one surgeon through 2.2 mm incision in the upper corneal limbus. The hydroimplantation of IOL to the capsular bag was performed in all cases. |
| Measure | Description | Time Frame |
|---|---|---|
| To compare refractive outcomes in PEX and control eyes. | To measure MAE, MedAE, percentage of eyes within certain range of prediction error after cataract surgery | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| To determine whether any of IOL power prediction formulas is more precise for these challenging eyes. | To measure the effects of IOL power calculation formulas - SRK/T, Barrett Universal II and Hill-RBF - on postoperative refraction | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients above 18 yo with senile cataract with/without PEX without coexisting ocular pathologies
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| Name | Affiliation | Role |
|---|---|---|
| Tomasz Żarnowski, MD, PhD, Professor | Medical University in Lublin | Study Chair |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34561548 | Derived | Wlaz A, Kustra A, Rozegnal-Madej A, Zarnowski T. Intraocular lens power calculations in eyes with pseudoexfoliation syndrome. Sci Rep. 2021 Sep 24;11(1):19071. doi: 10.1038/s41598-021-98675-5. |
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| ID | Term |
|---|---|
| D012030 | Refractive Errors |
| D002386 | Cataract |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
| D007905 | Lens Diseases |
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