Impact of Exercise on Muscle Metabolism and Function for Persons With Parkinsons | NCT07720713

NCT07720713

Overview

NCT ID: NCT07720713
Lead Sponsor: University of Texas Southwestern Medical CenterOTHER
Official Title: Assessment of Muscle Metabolism Using Magnetic Resonance Spectroscopy With Clinical Strengthening in Parkinson's Disease
Brief Summary: This investigation assesses the impact of a strengthening program on muscle metabolism in the gastrocnemius muscle (GM) and is an essential step in the establishment of future clinical intervention for the GM in people with Parkinson's disease (with healthy peers as the control group). The participants will be provided with a progressive GM strengthening program while monitoring muscle metabolism and functional changes before and after intervention.
Conditions: Parkinson
Interventions

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion Criteria:

50-80 years of age, males and females, individuals with and without PD

Hoehn and Yahr stages 1- 4 (if diagnosed with PD)

Bilateral Heal Raise - minimum of 10 repetitions

Exclusion Criteria:

Unable to walk for >5 minutes at a time with or without an assistive device

Any comorbidity limiting exercise