This study includes adults with multiple myeloma or B-cell lymphoma who were/will be treated with CAR-T cell therapy at the IRCCS Azienda Ospedaliero-Universitaria di Bologna. The aim is to better understand infections that may occur during the first year after CAR-T treatment, including how often they happen, their causes, and factors that may increase the risk. The study will use information from patients treated in the past and from newly enrolled patients. For some patients who develop fever after CAR-T therapy, a rapid molecular blood test will be used alongside standard tests to help identify bloodstream infections more quickly and support timely clinical care.
Inclusion Criteria:
Exclusion Criteria:
zeno.pasquini@aosp.bo.it+39 051 214 3752
Adult patients (≥18 years old) diagnosed with relapsed/refractory multiple myeloma or B-cell non-Hodgkin lymphoma who receive CAR-T cell therapy at the IRCCS AOUBo during the study periods
maddalena.giannella@unibo.it+39 051 2143199
Molecular-genetic Characterization in Patients Undergoing CAR-T Cell Infusion
Tissue Study in Patients Undergoing CAR-T Cell Therapy (CAR_21_01)
CAR-T Immunomonitoring in Multiple Myeloma (CART I5M)
CAR-T Cells in the Treatment of Malignant Hematological Tumors
Immunological Profile for Patients Treated With CAR-T Cells
Treatment of Hematological Malignancy With Novel CAR-T Cells.
A Study of CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies
Clinical Study of Multi-targeted CAR-T Therapy in Patients With Relapsed/Refractory B-Cell Lymphoma