Google Maps

NCT07713316

Overview

NCT ID: NCT07713316
Lead Sponsor: Brigham Young UniversityOTHER
Official Title: Understanding the Paradoxical Rise in Blood Glucose in the Context of a Low-carbohydrate Diet
Brief Summary: The purpose of this project was to elucidate the phenomenon of elevated blood glucose in the context of dietary carbohydrate restriction. Accordingly, we sought to quantify glucagon, and related hormones, between individuals that are adhering to a low-carbohydrate diet that manifests with normal vs. elevated glucose. Moreover, we sought to test the dynamic effect of macronutrients on these same outcomes. Each participant completed 3 testing periods that included the consumption of a glucose drink, protein drink, or fat (olive oil) drink in a random order and separated by at least 2 days. Each drink was matched for volume and total calories and bloodwork was taken every 30 minutes to assess the outcomes of interest.
Conditions: Elevated Blood Glucose
Low-carbohydrate Diet

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

weight stable (± 3% body weight) for the past 3 months

adhering to a low-carbohydrate (50g carbohydrates or less per day) diet at least 2 weeks prior to and during the duration of the one-month study

Exclusion Criteria:

unwilling to provide written consent

diagnosed with chronic disease(s) including cardiac disease, cancer, or liver disease,

pregnant or lactating,

taking medications that alter metabolism,

allergies to latex, cow's milk/milk products, olives, chlorhexidine, or dextrose,

have had more than 5 x-rays in the past year.