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Postoperative endoscopic polyp recurrence correlation of colorectal cancer: a retrospective cohort open-label study
This study aims to address the gaps in existing research by focusing on the high-risk group of colorectal cancer patients post-radical surgery, systematically reviewing potential factors influencing polyp recurrence, further clarifying independent risk factors for postoperative polyp recurrence in this population, and constructing a predictive model that better aligns with the clinical needs of such patients, thereby providing more precise references for developing personalized follow-up strategies in clinical practice.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Postoperative endoscopic polyp recurrence of colorectal cancer | Corhort of colorectal cancer patients undergoing colonoscopy follow-up after surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endoscopic polypectomy | Procedure | Endoscopic polypectomy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Adenoma recurrence after colorectal surgery | Postoperative colonoscopy review of colorectal cancer patients reveals adenoma recurrence | Postoperativeï¼›follow up till 5 years |
| Colitisafter colorectal surgery | Postoperative colonoscopy review of colorectal cancer patients reveals adenoma recurrence | Postoperativeï¼›follow up till 5 years |
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Inclusion Criteria:
Patients who underwent radical surgery for colon cancer at Gansu Provincial People's Hospital from January 2015 to December 2024 and regularly completed colonoscopy follow-up after surgery were selected as the research subjects. Inclusion criteria:
Diagnosed with colon cancer through histopathological examination ; Undergoing radical R0 resection ï¼› Complete Colonoscopy follow-up after surgery less than 12 months.
Exclusion Criteria:
With adenomatous polyposis , Lynch syndrome and Peutz-Jeghers syndromeï¼› Combined inflammatory bowel disease; Polyp were present before surgery and have not been completely removedï¼› With distant metastasis or local recurrenceï¼› Clinical data is missing and can not be analyzed.
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Patients who underwent radical surgery for colon cancer at Gansu Provincial People's Hospital from January 2015 to December 2024 and regularly completed colonoscopy follow-up after surgery were selected as the research subjects.After the completion of the prediction model construction, we will include 3-5 external queues for external validation.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gansu provincial hospital | Lanzhou | Gansu | 730000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36037595 | Background | Galjart B, Hoppener DJ, Aerts JGJV, Bangma CH, Verhoef C, Grunhagen DJ. Follow-up strategy and survival for five common cancers: A meta-analysis. Eur J Cancer. 2022 Oct;174:185-199. doi: 10.1016/j.ejca.2022.07.025. Epub 2022 Aug 27. | |
| 42320508 | Result | IJspeert JEG, Bretthauer M, Jover R, Dekker E; Dutch colonoscopy surveillance working group. Balancing benefit and burden: rethinking post-polypectomy colonoscopy surveillance strategies. Lancet Gastroenterol Hepatol. 2026 Jun 19:S2468-1253(26)00128-7. doi: 10.1016/S2468-1253(26)00128-7. Online ahead of print. |
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D011127 | Polyps |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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| 41195479 | Result | Ebert MP, Reichermeier S, Klug L, Lynen Jansen P, Pox C. Clinical Practice Guideline: Colorectal Cancer-Diagnosis, Treatment, Prevention, and Long-Term Follow-Up Care. Dtsch Arztebl Int. 2025 Dec 26;122(26):729-734. doi: 10.3238/arztebl.m2025.0196. Epub 2025 Dec 26. |
| 40774589 | Result | Laven-Law G, Symonds EL, Simpson K, Coats M, De Silva M, Hollington P, Cock C, Wassie MM. Risk of Advanced Colorectal Neoplasia at Follow-up Colonoscopy After Synchronous Adenoma and Clinically Significant Serrated Polyp. Clin Gastroenterol Hepatol. 2026 Feb;24(2):544-553. doi: 10.1016/j.cgh.2025.07.023. Epub 2025 Aug 5. |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |