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The goal of this observational study is to compare objective parameters of skin barrier function between healthy adult women who regularly use UV lamps during nail treatments and women who do not use UV lamps.
The main questions it aims to answer are:
Researchers will compare women who regularly use UV lamps during nail treatments with women who have natural nails and do not regularly expose their hands to UV lamps.
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Regular UV Nail Lamp Users | Healthy adult women who regularly undergo nail treatments involving exposure to UV lamps. | ||
| Non-Users of UV Nail Lamps | Healthy adult women who do not regularly undergo nail treatments involving exposure to UV lamps and have natural nails. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in Transepidermal Water Loss (TEWL) | Skin barrier function will be assessed by measuring transepidermal water loss using a Tewameter TM 300 probe. Values will be expressed in g/m²/h | Day 1 (single study visit) |
| Change in Skin Hydration | Hydration of the stratum corneum will be assessed using a Corneometer CM 825 probe. | Day 1 (single study visit) |
| Change in Skin Erythema | Skin erythema will be assessed using a Mexameter MX 18 probe. | Day 1 (single study visit) |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy adult women recruited from the general population. Participants will be classified into two groups based on their self-reported use of UV nail lamps during nail treatments: regular users of UV nail lamps and women who do not regularly use UV nail lamps and have natural nails.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Josipa Bukić | Contact | +385917933753 | jbukic@mefst.hr |
| Name | Affiliation | Role |
|---|---|---|
| Josipa Bukić | University of Split, School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Split School of Medicine | Recruiting | Split | 2100 | Croatia |
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| ID | Term |
|---|---|
| D004890 | Erythema |
| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D012877 | Skin Manifestations |
| D012816 | Signs and Symptoms |
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| D013568 | Pathological Conditions, Signs and Symptoms |