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| Name | Class |
|---|---|
| University Grenoble Alps | OTHER |
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The aim of this protocol is to assess physiological responses during various physical exercise protocols (whole-body exercise such as cycling or treadmill running, or localised exercise such as knee extension) and during inhalation of a gas mixtures with various oxygen contents (similar to exposure at high altitude).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exercise and hypoxia | Experimental | Exercise test performed while inhaling a gas mixture |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise and hypoxia | Combination Product | Subjects will perform an exercise test while inhaling a hypoxic gas mixture |
|
| Measure | Description | Time Frame |
|---|---|---|
| Muscle oxygenation | Measured by NIRS in % saturation | During 5 minutes before starting the exercise test, continuously during the exercise test and during 10 minutes immediatly after the end of the exercise test |
| Measure | Description | Time Frame |
|---|---|---|
| Gas exchange | Oxygen consumption and cardon dioxide production measured at the mouth, measured in ml/min | During 5 minutes before starting the exercise test, continuously during the exercise test and during 10 minutes immediatly after the end of the exercise test |
| Heart rate |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Samuel Vergès | Contact | +33670395773 | sverges@chu-grenoble.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CReSI (centre de recherche en santé intégrée) | La Tronche | 38700 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18081363 | Result | Mazzeo RS. Physiological responses to exercise at altitude : an update. Sports Med. 2008;38(1):1-8. doi: 10.2165/00007256-200838010-00001. | |
| 35168956 | Result | Hansford HJ, Wewege MA, Cashin AG, Hagstrom AD, Clifford BK, McAuley JH, Jones MD. If exercise is medicine, why don't we know the dose? An overview of systematic reviews assessing reporting quality of exercise interventions in health and disease. Br J Sports Med. 2022 Jun;56(12):692-700. doi: 10.1136/bjsports-2021-104977. Epub 2022 Feb 15. |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D000860 | Hypoxia |
| ID | Term |
|---|---|
| D001519 | Behavior |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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Measured by ECG in bpm |
| During 5 minutes before starting the exercise test, continuously during the exercise test and during 10 minutes immediatly after the end of the exercise test |
| Limb blood flow | Measured by Doppler ultrasound in ml/min | During 5 minutes before starting the exercise test, continuously during the exercise test and during 10 minutes immediatly after the end of the exercise test |