Cannabis Effects on Opioid Self-Administration

Impact of Cannabis on Opioid Self-Administration

The study will enroll participants with opioid use disorder and participants will reside at the University of Kentucky Hospital for this 6-week inpatient trial. During this time, double-blind doses of cannabis and opioids will be administered. The goal of the project is to determine if cannabis can alter the drive/desire to take opioids.

Inclusion Criteria:

• Participants with moderate to severe opioid use disorder who experience opioid withdrawal
• No allergies or adverse reactions to cannabis or opioids
• Willing to stay inpatient at the UK Hospital research center for approx. 6 weeks

Exclusion Criteria:

• Individuals seeking treatment for opioid use disorder