The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.

The main approach to OA management is pain control. Cryoneurolysis versus radiofrequency in decreasing knee pain.

Inclusion Criteria:

1. adults between the ages of 30 and 70 years with a clinical diagnosis of refractory knee OA who suffered from knee pain.
2. Patients who cannot afford intra-articular injections.
3. patients who had failed 2 different oral pain medications, and 6 weeks of physical therapy.

Exclusion Criteria:

1. Patients with OA show improvement in pain after physiotherapy.
2. patients evaluated by an orthopedic surgeon and deemed to be surgical candidates due to knee pathologies other than OA.
3. pregnant patients.
4. patients on anticoagulation therapy, who were not permitted to stop anticoagulation.
5. patients with previous trauma, neurological or endocrine diseases like diabetes mellitus, and knee tumors; and patients with inflammatory arthritis.
6. people who had received an intra-articular knee injection within the last 6 months.
7. Patients with tendon tears, bursitis, or calcified tendonitis as proven by imaging.

Plan to Share IPD: "Yes" Plan Description: "Data obtained through this study may be provided to qualified researchers with academic interest in scapular dyskinesis. Data or samples shared will be coded, with no PHI included. Approval of the request and execution of all applicable agreements (i.e., a material transfer agreement) are prerequisites to the sharing of data with the requesting party.

Results will be published by the investigators in academic journal.

Data requests can be submitted starting 9 months after article publication and the data will be made accessible for up to 24 months. Extensions will be considered on a case-by-case basis

Access to trial IPD can be requested by qualified researchers engaging in independent scientific research and will be provided following review and approval of a research proposal and Statistical Analysis Plan (SAP) and execution of a Data Sharing Agreement (DSA).

This is a prospective, randomised study. The closed envelop randomization method will be used for the randomization of the patients who will be also blinded to group allocation.