Use of Extracorporeal Photopheresis in Kidney Transplantation: Effects on Antibody-Mediated Rejection

Use of Extracorporeal Photopheresis in Kidney Transplantation: Effects on Antibody-Mediated Rejection

This study aims to describe, over a one-year period, the clinical, biological, and histological evolution of a cohort of kidney transplant recipients who developed antibody-mediated rejection and were treated with extracorporeal photopheresis.

Inclusion Criteria:

• Kidney transplant recipients followed at the University Hospitals of Besançon and Lille between September 1, 2016, and August 31, 2023
• Patients with antibody-mediated rejection (as confirmed by histological analysis of the renal biopsy)
• Rejection treated with extracorporeal photopheresis
• Subjects who do not object to the use of their personal data and/or biological samples
• Subjects affiliated with, or beneficiaries of, the French social security system

Exclusion Criteria:

• Patients with acute rejection
• Pregnant women, women in labor, or breastfeeding mothers
• Individuals deprived of liberty by judicial or administrative decision; individuals receiving compulsory psychiatric care; or individuals admitted to a healthcare or social institution for reasons other than research participation
• Minors
• Adults under legal protection or unable to provide informed consent
• Subjects without health insurance coverage
• Subjects currently within an exclusion period from another study, or as listed in the "national volunteer registry"