Effects of Magnesium and Spinning Training on Echocardiographic, Inflammatory, and Aerobic Outcomes

Effects of Magnesium Supplementation and Spinning Training on Cardiac Function, Oxidative Stress, Inflammation, and Aerobic Capacity

Regular aerobic exercise may improve cardiorespiratory fitness while modulating systemic inflammation and oxidative stress. Spinning, as a structured indoor cycling modality, provides a practical aerobic exercise model with adjustable intensity and duration, but its effects on redox balance, inflammatory status, aerobic capacity, and cardiac functional parameters may vary according to individual recovery and nutritional status. Magnesium is an essential micronutrient involved in energy metabolism, muscle contraction-relaxation, ion regulation, and inflammatory and oxidative pathways; therefore, magnesium use may be relevant to exercise adaptation and recovery.

This study aims to evaluate the associations of magnesium use and spinning training with oxidative stress, inflammation, aerobic capacity, and cardiac parameters. In this context, biochemical markers related to oxidative/antioxidant status and inflammation, aerobic performance indicators, and echocardiographic cardiac function parameters will be assessed together. The study is expected to provide real-world evidence on whether magnesium use in individuals participating in spinning training is associated with more favorable redox, inflammatory, aerobic, and cardiac profiles.

Inclusion Criteria:

• Self-identified male participants
• Aged 18 to 30 years
• Physically active individuals
• Participants who are eligible to participate in a structured spinning training program
• Participants with available baseline and follow-up assessments for biochemical, aerobic capacity, and cardiac function parameters

Exclusion Criteria:

• Presence of any chronic systemic disease
• Acute infection during the study period
• Regular use of anti-inflammatory or antioxidant medications
• Use of antioxidant or ergogenic supplements other than magnesium
• Any cardiovascular, musculoskeletal, or neurological condition that may limit participation in spinning training
• Missing baseline or follow-up outcome data