This comparative educational intervention study evaluated the educational effectiveness of artificial intelligence-generated patient information material on acne vulgaris among early-year medical students. In the first phase, acne vulgaris information texts were generated using different artificial intelligence models and evaluated by two dermatologists using quality and understandability assessment tools. In the second phase, the best-performing artificial intelligence-generated material was compared with standard human-generated material from the Turkish Dermatology Association and a control group. A total of 190 first- and second-year medical students at Erciyes University Faculty of Medicine participated in the study. Participants were divided into three groups: artificial intelligence-generated material group, Turkish Dermatology Association material group, and control group. After the educational materials were presented, participants completed a 12-question knowledge assessment questionnaire on acne vulgaris.

Inclusion Criteria:

• First- and second-year medical students enrolled at Erciyes University Faculty of Medicine
• Voluntary participation in the study
• Provision of informed consent

Exclusion Criteria:

• Students who declined to participate
• Students who did not complete the knowledge assessment questionnaire
• Students with incomplete study data

Individual participant data will not be publicly shared due to privacy and ethical considerations. De-identified data may be available from the corresponding author upon reasonable request.