Pistacho and Sleep Quality

Effect of Pistachio (Pistacia Vera L.) Consumption on Locomotor Activity and Molecular Regulation of the Circadian Clock in Adipose Tissue of Overweight Adults

The goal of this study is to evaluate the effect of pistachio (Pistacia vera L.) consumption on plasma melatonin, antioxidant capacity, and circadian rhythms in overweight young adults.

The main question it aims to answer are:

• Can the consumption of pistachios, specifically their content of compounds like phyto-melatonin, effectively regulate the human biological clock and circadian rhythms?

This study will provide scientific evidence supporting the biological clock-regulating action of compounds present in pistachios, such as phyto-melatonin, their impact on circadian rhythm regulation, and improvement of metabolic processes altered during obesity.

Inclusion Criteria:

• No diagnosed diseases
• Not regularly taking medications that affect melatonin synthesis or body regulation.

Exclusion Criteria:

• Smokers
• Pregnant women
• Individuals with night shifts, those following special diets or taking weight loss supplements
• People who had undergone recent surgical procedures or significant weight loss in two months before the study.
• Those taking sleep medications.
• Individuals who had made trans meridian trips within 1 month of the evaluation,
• Individuals with allergies, intolerances, or aversions to nuts/pistachios
• Participants who voluntarily withdrew from the study
• Participants who tested positive for COVID-19 during the intervention
• Participants who experienced adverse effects.