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The aim of this study is to evaluate the effects of adding 5-mcg dexmedetomidine to hyperbaric bupivacaine in our population as it has never been published before, to enhance the duration of analgesia after perianal procedures requiring spinal saddle block and, thus reducing requirements of postoperative analgesics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dexemedetomidine | Experimental | Experimental group received intrathecal dexmedetomidine 5 microgram added to 5 mg of 0.5% hyperbaric bupivacaine in dextrose injection |
|
| Hyperbaric bupivacaine | Active Comparator | Active comparator had 5 mg of 0.5% hyperbaric bupivacaine in dextrose injection alone |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexmedetomidine | Drug | dexmedetomidine 5 microgram added to 5 mg of 0.5% hyperbaric bupivacaine in dextrose injection |
|
| Measure | Description | Time Frame |
|---|---|---|
| Duration of analgesia | duration of analgesia was assessed from induction of anesthesia till patient discharge | 0 hour to 4 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Pain score | Pain will be assessed using Numeric Rating Scale (NRS) scale ranging from 0-10; 0 being no pain and 10 indicates the worst pain | Two hours post surgery till 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Liaquat National Hospital | Karachi | Pakistan |
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| Label | URL |
|---|---|
| Effects of Adding Intrathecal Dexmedetomidine to Hyperbaric Bupivacaine for Saddle Spinal Block in Adults Undergoing Peri-anal Surgeries | View source |
| Effect Of Dexmedetomidine Added To Intrathecal Hyperbaric Bupivacaine Versus Bupivacaine Alone On Mean Postoperative Analgesia After Spinal Saddle Block | View source |
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| ID | Term |
|---|---|
| D020927 | Dexmedetomidine |
| ID | Term |
|---|---|
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| Hyperbaric bupivacaine % 0.5 | Drug | 5 mg of 0.5% hyperbaric bupivacaine in dextrose injection alone |
|
| EFFECT OF ADDING DEXMEDETOMIDINE VERSUS FENTANYL TO INTRATHECAL HYPERBARIC BUPIVACAINE ON SPINAL BLOCK FOR INFRAUMBILICAL ELECTIVE SURGERIES | View source |
| Effects of intravenous dexmedetomidine on hyperbaric bupivacaine spinal anesthesia: A randomized study | View source |