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| ID | Type | Description | Link |
|---|---|---|---|
| F20581 | Other Grant/Funding Number | The Peanut Institute Foundation |
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The aim of this randomized interventional trial is to understand the effects of peanut consumption on patients with metabolic associated fatty liver. The main goal is to investigate if patients who consume peanuts have improved liver marker tests as well as metabolic profile. We will also investigate how peanuts alter the gut microbes and liver fat content in patients with metabolic associated fatty liver.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Peanut | Experimental | MASLD patients will consume 50 gm of peanut daily for 12 weeks |
|
| Control | No Intervention | Regular diet |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Peanut consumption | Other | MASLD patients will consume 50 gm of peanut daily for 12 weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hepatic Markers | Changes in hepatic markers such as ALT, ASP, ALP will be evaluated through blood tests at baseline and post-intervention | Baseline to post-intervention (12 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Metabolic Profile | Investigate change in metabolic profiles i.e., total cholesterol, HDL-C, LDL-C, triglycerides, glucose, hemoglobin A1C (HBA1C), and insulin over 12 weeks | Baseline to post-intervention (12 weeks) |
| Gut microbiota composition |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Menghua Tao, PhD | Contact | 313-590-9408 | mtao1@hfhs.org |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Henry Ford Health System | Recruiting | Detroit | Michigan | 48202 | United States |
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| ID | Term |
|---|---|
| D005234 | Fatty Liver |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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Investigate whether MASLD patients in the Peanut arm will have improved gut microbiota compositions than those in the Control arm
| Baseline to post-intervention (12 weeks) |
| Intrahepatic fat content | Explore whether MASLD patients in the Peanut arm may have lower intrahepatic fat content (IHF) than those in the Control arm over 12 weeks | Baseline to post-intervention (12 weeks) |