Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction

Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry

The goal of this randomized clinical trial is to assess whether BCP (Biphasic Calcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction. The main question it aims to answer is whether using BCP for alveolar ridge preservation has a positive effect on bone volume compared with natural healing.

The main questions it aims to answer are:

Does BCP improve ridge preservation compared with natural healing?

Researchers will compare BCP grafted sockets to natural healing sockets to see if BCP better preserves ridge volume.

Participants will:

Have a tooth indicated for extraction.

Be assigned to either BCP or natural healing.

Undergo CBCT (Cone Beam Computed Tomography) and intra-oral scanning after extraction and after six months of healing to measure horizontal and vertical resorption and bone density.

Inclusion Criteria:

• 18 years or older
• Acceptance of informed consent
• Type 1 or 2 extraction sockets (Elian et al. 2007)

Exclusion Criteria:

• Presence of active infection or severe inflammation in the intervention zone
• Relevant medical history that contraindicates implant surgery
• Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score >15%) and lack of motivation
• Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%)
• Uncontrolled and /or untreated periodontal disease
• Heavy smokers (more than 10 cigarettes per day)
• Immunosuppression