Alcohol Sensitivity Among Older Adults Who Consume Alcohol

Individual Differences in Alcohol Sensitivity

This is a proof-of-concept study exploring individual differences in sensitivity to alcohol among older healthy current drinkers aged 65 to 80. Participants will complete two sessions during which they will complete questionnaires and laboratory measures of mental abilities and brain activity and receive a beverage that may or may not contain a moderate dose of alcohol.

As a preliminary, proof-of-concept study, the project is designed to provide information regarding variability in response to a moderate dose of alcohol among healthy men and women who are current drinkers and aged 65 to 80. It is expected that approximately 75 individuals will complete the study. Participants complete two laboratory sessions. Each session will include consuming a beverage that may or may not include alcohol. If the beverage does include alcohol, the volume will not exceed the amount that a drinker might consume in 1 to 2 drinks. The outcomes will provide information regarding the how older adults vary in their response to alcohol and explore whether alcohol sensitivity is related to selected measures of cognition.

Inclusion Criteria

• Alcohol Drinkers who consume alcohol on a regular basis
• No history of significant substance misuse
• at least 12 years of education or GED equivalence Exclusion Criteria
• current Cigarette smoker
• Type 1 Diabetes or uncontrolled Type 2 Diabetes
• Epilepsy
• Neurodegenerative disorder
• Significant psychiatric disorder such as a psychotic disorder, bipolar disorder, current major depression or PTSD